Folklore Clinical Variant Interpretation

Helena Bioinformatics MCP for clinical variant interpretation, ACMG/AMP evidence and literature.

Use Streamable HTTP. Folklore does not require an account, API key or OAuth flow.

search_variant_evidence, search_variant_literature, get_publication_details

io.github.helena-bioinformatics/folklore

Every client below reaches the same endpoint and tool. A tested custom connection means that Folklore was connected in that client. It does not mean the provider has approved a public directory listing.

Create a custom MCP app and use the Folklore endpoint. No authentication fields are required.

Add a custom connector with the Folklore endpoint. The connection does not require an account or API key.

Add a server named folklore with the url field shown below.

Add a server named folklore with type http and the Folklore endpoint as its url.

Add a server named folklore in the Gemini CLI MCP settings, select HTTP transport and use the Folklore endpoint.

Use the same endpoint in the client remote MCP or custom connector settings. Select Streamable HTTP when the client asks for a transport.

{ "mcpServers": { "folklore": { "url": "https://api.helena.bio/folklore/v1/mcp" } } }

{ "servers": { "folklore": { "type": "http", "url": "https://api.helena.bio/folklore/v1/mcp" } } }

These pages were publicly reachable when this guide was reviewed on 13 August 2026. The Official MCP Registry is the canonical machine-readable publication source. Aggregator health labels do not replace the Folklore health and readiness checks.

Canonical registry identity io.github.helena-bioinformatics/folklore. Version 1.2.2 is the current published release.

The listing is owned by Helena Bioinformatics and uses the canonical Folklore endpoint.

Automatically discovered listing. Registry metadata can take time to refresh after a release.

Editorially approved public listing. Its durable slug remains stable while the display-name update is processed.

Submission is recorded separately from publication. The links below show the durable public review item where one exists. ChatGPT and Claude directory submissions are complete, but public directory approval has not been independently verified. Smithery publication is deferred.

Example: Use Folklore to classify ENST00000226413.5:c.317A>G under ACMG/AMP and summarize the evidence, provenance and limitations.

Supported input includes GRCh38 coordinates, selected genomic, coding and protein HGVS, SPDI and rsID for one nuclear germline SNV or simple indel smaller than 50 base pairs. Ambiguous expressions return candidates for the user to choose.

Folklore returns variant-level decision support for qualified genetics professionals. It accepts no patient, phenotype, family, segregation or case context. The automated classification is not a diagnosis, treatment recommendation or standalone clinical report.

A qualified professional must review the evidence and confirm clinically significant findings before clinical use.

Transaction-complete hotel booking over MCP — 300K+ properties, real hotel confirmation numbers, loyalty points, secure checkout. Hotels are merchant of record. Builders set their own booking fee via Stripe Connect. Built on proven distribution infrastructure.

An MCP server for AI video generation. MCP server for AI video generation. Lets Claude, ChatGPT, OpenClaw , Hermes & other agents create AI videos and publish them to YouTube, TikTok, Instagram etc..

Institutional research and manager diligence reports on hedge funds, venture capital and private equity managers. Summary of filings, personnel changes, media screening and social signals delivered to you in minutes.

ALTER - identity infrastructure for the AI economy

D2C eCommerce fulfillment platform: manage orders, inventory, shipments, campaigns, and billing via AI agents

Apigene MCP Gateway is the runtime layer that connects AI agents to APIs and MCP servers via Model Context Protocol.

MCP to interface with multiple blockchains, staking, DeFi, swap, bridging, wallet management, DCA, Limit Orders, Coin Lookup, Tracking and more.

MCP server for Bitnovo Pay integration with AI agents. Provides cryptocurrency payment capabilities through Bitnovo Pay API. Features include payment creation, status checking, QR code generation, and webhook management with support for multiple tunnel providers (ngrok, zrok, manual).

Shop for gift cards, esims, phone topups. Pay with cards and crypto.

You built it, now get users! GoToMarket MCP server